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Brentford defender James Tarkowski will not feature after the defender missed Saturday's game against Burnley.
Manager Dean Smith hopes to keep midfielders Ryan Woods, Josh McEachran and Alan Judge together for the visit of Leeds.
The visitors could start ex-Brentford midfielder Toumani Diagouraga, who they signed on Monday from the London club.
United midfielder Alex Mowatt is out with a thigh injury but striker Chris Wood could return.
• Brentford are unbeaten in their past five meetings against Leeds, drawing three and winning two.
• Leeds have won just three of their 14 trips to Griffin Park in league competition (D6 L5).
• After scoring six goals in Dean Smith's first two home games, Brentford have scored just once in their last three.
• Leeds are looking for their first away victory of 2016, following two defeats and a draw in their three trips since the turn of the year.
• Leeds have failed to score a first half goal against Brentford in their last five meetings.