Chelsea will begin their Women's Super League title defence at newly promoted Doncaster Belles on Thursday, 24 March.
Doncaster, promoted as WSL 2 runners-up, make their top-flight return after being controversially demoted in 2014.
Reading, who come up as WSL 2 champions, face a double header away from home, starting at Arsenal before going to Sunderland three days later.
Manchester City, who narrowly missed out on the title last season, start their campaign against Notts County.
The season begins on Wednesday, 23 March with Liverpool hosting Birmingham City.
In a major change, the final for the revamped Continental Cup has been moved to October, meaning that the top-flight campaign will mark the end of the 2016 domestic league season.
The FA Cup final - to be hosted at Wembley Stadium for a second year - moves back to its traditional date in May.
Wednesday, 23 March
Liverpool v Birmingham City
Manchester City v Notts County
Arsenal v Reading
Thursday, 24 March
Doncaster Rovers Belles v Chelsea
Saturday, 26 March
Sunderland v Reading
In the second-tier, relegated and renamed Bristol City host West Country rivals Yeovil Town in their opening game.
Sheffield FC, the first team to be promoted to WSL from the Women's Premier League, kick-off against Durham.
Wednesday, 23 March
Bristol City v Yeovil Town
Sheffield FC v Durham
London Bees v Watford
Thursday, 24 March
Everton v Aston Villa
Oxford United v Millwall Lionesses
Saturday, 26 March
Bristol City v Sheffield FC
Sunday, 27 March
Aston Villa v Oxford United
Watford v Yeovil Town