Match ends, Manchester United 0, Juventus 1.
Cristiano Ronaldo marked his return to Old Trafford with a win as his Juventus side saw off Manchester United to move five points clear at the top of Champions League Group H.
The former United star helped to set up Juve's winner in the 17th minute, with his cross reaching Paulo Dybala who finished from close range.
The Italian champions had several chances to extend their lead during a first half where they were completely dominant, managing 10 shots to United's one and enjoying 70% of possession.
United improved after the break but only had one serious effort at goal, when Paul Pogba let fly from the edge of the area but saw his shot rebound off the post.
It was a frustrating night for United boss Jose Mourinho, who was taunted by the away fans as he saw his side suffer only their second home European defeat since March 2013, when Ronaldo scored Real Madrid's winner.
The two sides will meet again at the Allianz Stadium on 7 November, when a win will send Juve into the last 16.
United remain in second place, with their hopes of making the knockout stages boosted by Valencia's draw with Young Boys earlier on Tuesday.
More to follow.
Relive how Juventus beat Manchester United?
Match ends, Manchester United 0, Juventus 1.
Second Half ends, Manchester United 0, Juventus 1.
Attempt blocked. Cristiano Ronaldo (Juventus) right footed shot from outside the box is blocked. Assisted by Blaise Matuidi.
Attempt saved. Anthony Martial (Manchester United) right footed shot from outside the box is saved in the bottom right corner. Assisted by Nemanja Matic.
Attempt missed. Leonardo Bonucci (Juventus) right footed shot from outside the box is too high. Assisted by Miralem Pjanic.
Corner, Juventus. Conceded by Victor Lindelöf.
Foul by Blaise Matuidi (Juventus).
Chris Smalling (Manchester United) wins a free kick in the defensive half.
Substitution, Juventus. Douglas Costa replaces João Cancelo.
Offside, Manchester United. Marcus Rashford tries a through ball, but Juan Mata is caught offside.
Hand ball by Cristiano Ronaldo (Juventus).
Corner, Manchester United. Conceded by Leonardo Bonucci.
Attempt blocked. Romelu Lukaku (Manchester United) left footed shot from the left side of the box is blocked. Assisted by Anthony Martial.
Offside, Juventus. Miralem Pjanic tries a through ball, but Federico Bernardeschi is caught offside.
Giorgio Chiellini (Juventus) is shown the yellow card.
Miralem Pjanic (Juventus) wins a free kick in the defensive half.
Foul by Ashley Young (Manchester United).
Substitution, Juventus. Andrea Barzagli replaces Juan Cuadrado.
Foul by Rodrigo Bentancur (Juventus).
Marcus Rashford (Manchester United) wins a free kick on the left wing.
Hand ball by Giorgio Chiellini (Juventus).
Leonardo Bonucci (Juventus) wins a free kick in the defensive half.
Foul by Marcus Rashford (Manchester United).
Substitution, Juventus. Federico Bernardeschi replaces Paulo Dybala.
Ashley Young (Manchester United) is shown the yellow card.
Alex Sandro (Juventus) wins a free kick in the defensive half.
Foul by Ashley Young (Manchester United).
Paul Pogba (Manchester United) hits the left post with a left footed shot from outside the box.
Cristiano Ronaldo (Juventus) wins a free kick in the defensive half.
Foul by Chris Smalling (Manchester United).
Rodrigo Bentancur (Juventus) wins a free kick in the defensive half.
Foul by Anthony Martial (Manchester United).
Offside, Juventus. Cristiano Ronaldo tries a through ball, but Paulo Dybala is caught offside.
Paulo Dybala (Juventus) wins a free kick in the defensive half.
Foul by Ashley Young (Manchester United).
Blaise Matuidi (Juventus) is shown the yellow card for a bad foul.
Foul by Blaise Matuidi (Juventus).
Ashley Young (Manchester United) wins a free kick on the right wing.
Offside, Manchester United. Juan Mata tries a through ball, but Nemanja Matic is caught offside.
Foul by Rodrigo Bentancur (Juventus).