Lowland League side East Kilbride set up a home Scottish Cup meeting with Celtic with victory over Lothian Thistle Hutchison Vale.
Jack Smith's stunning half-volley settled Kilby just before half-time, although the visitors had earlier hit the crossbar through Willis Hare.
East Kilbride goalkeeper Matt McGinley denied Hare after the break with a great diving save.
And Sean Winter sealed a money-spinning fifth-round tie from close range.
Whether that match versus Celtic will be allowed to be played at the 500-or-so-capacity K Park remains to be seen, but the result has well and truly put East Kilbride on the map.
BSports Scotland will provide live television, online and radio coverage of the tie on 7 February and the revenue generated will have a significant impact on the club founded in 2010.
The hosts had failed to profit from their early dominance as Anthony Brady's mazy run left him one defender short of being clean through and Craig Hastings dragged a low shot wide of the far post.
Lothian Thistle HV from the East of Scotland League took Kilby's profligacy as encouragement. The hosts' goalkeeper Matt McGinley had to be sharp to deny Hare before the same striker struck the crossbar from 16 yards.
An injury to midfielder Ross Smith had East Kilbride rattled for a short spell but they got the crucial first goal shortly before the interval.
The visitors' stand-in keeper Byron Gibb had previously made a couple of decent saves, but had no chance when Smith lashed in from the edge of the box following a blundered defensive clearance.
Scott Gormley missed a half-chance for Lothian Thistle HV early in the second half and it did not take long for Kilby's Brady to cause more problems with his dribbling.
Smith had the opportunity to double his tally but fired wide of the near post.
In the meantime, East Kilbride captain Barry Russell chose to try and change his boots and ended up playing the majority of the second half with one black and one green one.
Hare continued to be Lothian Thistle HV's main threat and McGinley pulled off a brilliant low save to turn the striker's shot round the post.
And the home team could afford to start thinking about their meeting with the Scottish champions in earnest when the seasoned Winter demonstrated his predatory instinct to poke the ball home following an 86th-minute corner.
Full Time Match ends, East Kilbride 2, Lothian Thistle Hutchison Vale 0.
90:00 +3:08 Full timeFull Time Second Half ends, East Kilbride 2, Lothian Thistle Hutchison Vale 0.
86:13 Goal scoredGoal! Goal! East Kilbride 2, Lothian Thistle Hutchison Vale 0. Sean Winter (East Kilbride) left footed shot from very close range to the centre of the goal following a corner.
85:49Corner, East Kilbride. Conceded by Mathew Joint.
85:17Corner, East Kilbride. Conceded by Mathew Joint.
83:48Anthony Brady (East Kilbride) wins a free kick in the defensive half.
83:48Foul by Scott Gormley (Lothian Thistle Hutchison Vale).
80:10Barry Russell (East Kilbride) wins a free kick in the attacking half.
80:10Foul by Scott Moffat (Lothian Thistle Hutchison Vale).
78:38 SubstitutionSubstitution Substitution, East Kilbride. Liam Gormley replaces Craig Hastings.
76:25 SubstitutionSubstitution Substitution, Lothian Thistle Hutchison Vale. Liam O'Donnell replaces Willis Hare.
73:07 SubstitutionSubstitution Substitution, Lothian Thistle Hutchison Vale. Ryan Fox replaces Darren Smith.
72:04Corner, Lothian Thistle Hutchison Vale. Conceded by Matthew McGinley.
71:55Attempt saved. Willis Hare (Lothian Thistle Hutchison Vale) right footed shot from the left side of the box is saved in the bottom right corner.
68:16 BookingBooking Paul Crawford (Lothian Thistle Hutchison Vale) is shown the yellow card for a bad foul.
68:12Anthony Brady (East Kilbride) wins a free kick in the defensive half.
68:12Foul by Paul Crawford (Lothian Thistle Hutchison Vale).
67:09Corner, Lothian Thistle Hutchison Vale. Conceded by Bernard Coll.
63:15 BookingBooking Eddie Mearns (Lothian Thistle Hutchison Vale) is shown the yellow card for a bad foul.
63:13Anthony Brady (East Kilbride) wins a free kick in the attacking half.
Foul by Eddie Mearns (Lothian Thistle Hutchison Vale).
61:12Corner, Lothian Thistle Hutchison Vale. Conceded by Barry Russell.
60:49 SubstitutionSubstitution Substitution, Lothian Thistle Hutchison Vale. Scott Moffat replaces John-Ross Kerr.
60:01Attempt missed. Scott Stevenson (East Kilbride) header from the right side of the six yard box is close, but misses to the right following a corner.
59:39Corner, East Kilbride. Conceded by Dylan Moore.
59:01Corner, East Kilbride. Conceded by Paul Crawford.
52:42Attempt missed. Scott Gormley (Lothian Thistle Hutchison Vale) right footed shot from the centre of the box is close, but misses to the right.
47:30Corner, East Kilbride. Conceded by Scott-Taylor MacKenzie.
45:00Second Half begins East Kilbride 1, Lothian Thistle Hutchison Vale 0.
45:00 +1:19 Half timeHalf Time First Half ends, East Kilbride 1, Lothian Thistle Hutchison Vale 0.
45:00 +0:26Foul by Anthony Brady (East Kilbride).
45:00 +0:26Kevin Brown (Lothian Thistle Hutchison Vale) wins a free kick in the attacking half.
42:38Foul by Sean Winter (East Kilbride).
42:38John-Ross Kerr (Lothian Thistle Hutchison Vale) wins a free kick in the attacking half.
39:45 Goal scoredGoal! Goal! East Kilbride 1, Lothian Thistle Hutchison Vale 0. Jack Smith (East Kilbride) right footed shot from outside the box to the bottom left corner.
37:09Foul by Anthony Brady (East Kilbride).
37:09Eddie Mearns (Lothian Thistle Hutchison Vale) wins a free kick in the defensive half.
34:22Corner, East Kilbride. Conceded by Scott-Taylor MacKenzie.
33:10Attempt missed. Frazer Johnstone (East Kilbride) right footed shot from the centre of the box is too high following a corner.
32:31Corner, East Kilbride. Conceded by Eddie Mearns.
29:04Attempt missed. Jack Smith (East Kilbride) right footed shot from outside the box misses to the right.
27:20Corner, East Kilbride. Conceded by Byron Gibb.
27:14Attempt saved. Jack Smith (East Kilbride) right footed shot from the right side of the box is saved in the bottom right corner.
24:43 SubstitutionSubstitution Substitution, East Kilbride. Frazer Johnstone replaces Ross Smith because of an injury.
23:14Delay in match Scott Gormley (Lothian Thistle Hutchison Vale) because of an injury.
18:31 BookingBooking Darren Smith (Lothian Thistle Hutchison Vale) is shown the yellow card for a bad foul.
18:28Anthony Brady (East Kilbride) wins a free kick in the attacking half.
18:28Foul by Darren Smith (Lothian Thistle Hutchison Vale).
8:22Corner, East Kilbride. Conceded by Dylan Moore.
7:53Ross Smith (East Kilbride) wins a free kick in the attacking half.
7:53Foul by Paul Crawford (Lothian Thistle Hutchison Vale).
5:47Craig Hastings (East Kilbride) wins a free kick in the defensive half.
5:47Foul by John-Ross Kerr (Lothian Thistle Hutchison Vale).
4:27Attempt missed. Craig Hastings (East Kilbride) right footed shot from the centre of the box is close, but misses to the right.
3:22Attempt missed. Martin McBride (East Kilbride) right footed shot from outside the box is too high.
2:26Corner, East Kilbride. Conceded by Eddie Mearns.
1:34Corner, Lothian Thistle Hutchison Vale. Conceded by Barry Russell.
0:00First Half begins.
0:00Lineups are announced and players are warming up.
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