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Manchester United will be without striker Wayne Rooney and midfielder Morgan Schneiderlin for their crucial Champions League game at Wolfsburg.
Rooney, 30, remains out with the ankle injury that forced him to miss Saturday's 0-0 draw with West Ham.
Schneiderlin, 26, came off injured against the Hammers and will not travel to Germany for Tuesday's match.
United must win to be sure of advancing to the last 16 of Europe's premier club competition.
Louis van Gaal's team are second in Group B, one point ahead of Dutch side PSV Eindhoven, who have a superior head-to-head record having beaten United in the Netherlands and drawn 0-0 at Old Trafford.
Van Gaal will also be without injured defenders Phil Jones (ankle) and Marcos Rojo (shoulder), and midfielder Ander Herrera (hamstring).
United squad: De Gea, Romero, Blind, Borthwick-Jackson, Darmian, McNair, Smalling, Varela, Carrick, Fellaini, Goss, Lingard, Mata, Pereira, Powell, Schweinsteiger, Young, Martial, Memphis.