Coverage: Live text commentary on BSports website
Tottenham striker Harry Kane may be rested for their final Europa League group game against Monaco on Thursday.
Spurs, who have already qualified for the last 32, will secure top spot in Group J with a draw at White Hart Lane.
Midfield pair Nacer Chadli (ankle) and Nabil Bentaleb (foot) are back in the squad after injury, but fellow midfielder Mousa Dembele is ill.
Academy graduates Ryan Mason and Alex Pritchard (both ankle) remain unavailable.
England international Kane, 22, has been ever present for Spurs this season, scoring 10 goals in their 21 matches.
He also played every game of England Under 21s' dismal European Championship campaign in the summer.
"Is it a chance to rest him? Maybe yes," said Spurs manager Mauricio Pochettino.
"He is in the squad but it is true we need to assess him and we have to decide the starting 11."
Spurs host Newcastle in the Premier League on Sunday as they aim to continue their 14-match unbeaten top-flight run.
But Pochettino said he will not make wholesale changes for the visit of the French Ligue 1 side, who must win and hope Anderlecht fail to beat Qarabag to qualify.
"There may be one or two more changes but not much," said former Argentina international Pochettino.
"The squad we have is strong enough to compete in different competitions, but maybe if you compare the team to the game against Qarabag there will be some changes.
"It is a good opportunity to finish first and win the group."